Towards a personalized modeling of organs

Organoids are miniaturized self-assembling 3D cell cultures with complex tissue organization. They can be derived from stem cells, tumors or isolated tissue from primary mammalian organs. Although they are simplified organ models, they exhibit accurate functional and structural properties close to in vivo physiology. 

As an innovative and emergent Research Field, Organoids offer an alternative to animal models with personalized models of the organ of interest for the testing of new therapeutic molecules and new cell therapies.

Our project

As part of the InOc (International Organoid Contest) competition, organized by members of Aviesan (National Alliance for Life and Health Sciences), we have chosen to develop a new model of organoids culture on microfluidic chips. This method will be used to create two organ models:  the Adenohypophysis and the Retina.

Retinal Organoid