Michael Graupner (PhD)

Home
Last updated: Jan, 2026

I am a CNRS researcher (CRCN) in neuroscience, focusing on how neural circuits encode information and coordinate behavior. My work bridges experimental and computational approaches, combining electrophysiology, imaging, and modelling to understand brain network dynamics.

Since January 2025, I have been co-team leader of the Orientation and Coordination team at the SPPIN laboratory, together with my collaborator Desdemona Fricker.

Together Alex Cayco-Gajic (ENS), Srdjan Ostojic (ENS, CNRS), João Barbosa (Institute for Neuromodulation, Neurospin), we are organizing the Neural Networking Night.


Contact
Saints-Pères Paris Institute for the Neurosciences (SPPIN), CNRS UMR 8003
Université Paris Cité
office : H 367 - lab : E 363 or E 374
45 rue des Saints Pères
75270 Paris Cedex 06
France
phone : +33 1 76 53 43 20

My Google Scholar profile My Github profile My ORCID identifier


Reserach Interests
Small networks of neurons, called microcircuits, are the basic building blocks of brain computation, continuously integrating sensory inputs with internal representations to guide behavior. While these circuits have been studied extensively in isolated brain tissue, their role during natural behavior remains poorly understood. My research aims to uncover how specific neural circuits support motor control and spatial orientation in the intact brain. Using in vivo imaging, electrophysiology, and targeted circuit manipulations in both head-fixed and freely moving mice, I study population activity patterns linked to walking and head direction. These experimental approaches are combined with computational modeling to understand how neural interactions—particularly inhibitory circuits—give rise to precise movement control and stable internal representations of orientation (find more details in the research section of this website).


Biographical notes (Download a full CV as pdf here, as of January 2025)
Sep 2019 Habilitation à Diriger des Recherches (HDR)
Université Paris Descartes, France
  • HDR thesis and presentation title : "Bridging Modeling and Experimental Neuroscience"

  • since Oct 2015 CNRS Researcher (CRCN)
    Laboratoire de Physiologie Cérébrale, Université Paris Cité, France
  • investigating how brain circuits support motor control and spatial orientation in the intact brain using in vivo imaging, electrophysiology, and targeted circuit manipulations

  • Aug 2014 - Sep 2015 Post-Doc in experimental neuroscience
    Laboratoire de Physiologie Cérébrale, Université Paris Descartes, France
  • studying the link between calcium signaling and spiking activity of cerebellar molecular layer interneurons in the group of Isabel Llano

  • Aug 2009 - Jun 2014 Post-Doc in computational and experimental neuroscience
    Center for Neural Science, New York University, United States
  • working on signal integration and processing in the auditory cortex in the group of Alex Reyes

  • Nov 2007 - Jun 2009 Post-Doc in computational neuroscience
    Group for Neural Theory, LNC, ENS, INSERM, Paris, France
  • working on mechanisms underlying nicotine addiction in the group of Boris Gutkin

  • Jan 2004 - Jun 2008 PhD student in the framework of a binational promotion - "cotutelle"
    Laboratory of Neurophysics and Physiology, Paris V, France and Max-Planck-Institut für Physik komplexer Systeme, (TU Dresden), Germany
  • working on induction and maintenance of synaptic plasticity (download thesis)
  • supervisors: Nicolas Brunel (Paris) and Frank Jülicher (Dresden)

  • Oct 1997 - Jul 2003 Masters in Physics
    University of Technology Dresden, Germany
  • Diploma Thesis at the Institute for Theoretical Physics under the supervison of Michael Meyer-Hermann
  • studied one year at the University of Edinburgh, UK (Oct 2000 - Jun 2001)


  • Miscellaneous