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Michael Graupner (PhD)
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Saints-Pères Paris Institute for the Neurosciences (SPPIN), CNRS UMR 8003
Université Paris Cité office : H 367 - lab : E 363 or E 374 45 rue des Saints Pères 75270 Paris Cedex 06 France
Reserach Interests
Small networks of neurons, called microcircuits, are the basic building blocks of brain computation, continuously integrating sensory inputs with internal representations to guide behavior. While these circuits have been studied extensively in isolated brain tissue, their role during natural behavior remains poorly understood. My research aims to uncover how specific neural circuits support motor control and spatial orientation in the intact brain. Using in vivo imaging, electrophysiology, and targeted circuit manipulations in both head-fixed and freely moving mice, I study population activity patterns linked to walking and head direction. These experimental approaches are combined with computational modeling to understand how neural interactions—particularly inhibitory circuits—give rise to precise movement control and stable internal representations of orientation (find more details in the research section of this website).
Biographical notes (Download a full CV as pdf here, as of January 2025)
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